About MPS
- Mucopolysaccharidosis (MPS): a group of rare diseases caused by congenital defects in lysosomal enzymes1
- These enzymes are responsible for the degradation of glycosaminoglycans (GAGs)1
- In MPS, GAGs accumulate in different parts of the body because lysosomal enzymes are absent or non-functional. This causes multisystemic problems1
- Bone-related symptoms are among the first that MPS patients develop1. Therefore, the orthopedic surgeon is in a position to diagnose the disease
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- Lampe C. Rheumatology 2012;51:401–402
- Beck M et al. J Pediatr Rehabil Med 2010;3:39–46.